Effect of the general anesthetic halothane on the activity of the transverse tubule Ca<sup>2+</sup>-activated K<sup>+</sup> channel
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Effects of benzo(a)pyrene exposure on the ATPase activity and calcium concentration in the hippocampus of neonatal rats.
OBJECTIVES To investigate whether postnatal benzo(a)pyrene (B(a)P) exposure caused the impairments on the process of neurodevelopment and the alteration in the calcium medium in the neonatal rats. MATERIAL AND METHODS Eighty neonatal Sprague Dawley (SD) rats were randomly divided into 5 groups (untreated control group, vehicle group, 0.02 mg/kg, 0.2 mg/kg and 2 mg/kg B(a)P-exposed group). Rat...
متن کاملModification of the tonus and drug-induced contraction of the isolated rat ileum by removal of Na from bathing media.
Society, in Hiroshima, June 4, 1972. Abstract-Effect of removal of Na from bathing media on the tonus and contractile response to drugs of strips of the rat ileum was investigated. Removal of Na from the bathing media by replacing NaCl with sucrose or choline Cl produced a transient contraction, which was not altered by treatment with atropine. This contraction was attenuated when preparations ...
متن کاملNa<SUP>+</SUP>-K<SUP>+</SUP>ATPase in Human Brain Tumors
Na+-K+-stimulated adenosine triphosphat s (Na+-K+ATPase) activities were measured in 12 human brain tumors and surrounding tissue (white matter and cortex) by the colorimetric deter mination of hydrolyzed inorganic phosphorus (Pi) from adenosine triphosphate (ATP). In glioma cases, the brain microvessels, filial component, and neurons were isolated fr...
متن کاملThe Caenorhabditis elegans Iodotyrosine Deiodinase Ortholog SUP-18 Functions through a Conserved Channel SC-Box to Regulate the Muscle Two-Pore Domain Potassium Channel SUP-9
Loss-of-function mutations in the Caenorhabditis elegans gene sup-18 suppress the defects in muscle contraction conferred by a gain-of-function mutation in SUP-10, a presumptive regulatory subunit of the SUP-9 two-pore domain K(+) channel associated with muscle membranes. We cloned sup-18 and found that it encodes the C. elegans ortholog of mammalian iodotyrosine deiodinase (IYD), an NADH oxida...
متن کاملSolution of the 9th Homework
Proof. Let us first assume that c > 0. To prove that sup(cA) = c(sup A), we claim that sup(cA) ≤ c(sup A) and sup(cA) ≥ c(sup A). For the first inequality, let a′ ∈ cA be arbitrary. Then a′ = ca for some a ∈ A. But since a ≤ sup A, we have a′ = ca ≤ c(sup A). This shows that c(sup A) is an upper bound of cA, hence we have sup(cA) ≤ c(sup A). The reverse inequality also follows in a similar mann...
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